Air pollution and in utero programming of poor fetal growth
نویسندگان
چکیده
منابع مشابه
In Utero Programming of Later Adiposity: The Role of Fetal Growth Restriction
Intrauterine growth restriction (IUGR) is strongly associated with obesity in adult life. The mechanisms contributing to the onset of IUGR-associated adult obesity have been studied in animal models and humans, where changes in fetal adipose tissue development, hormone levels and epigenome have been identified as principal areas of alteration leading to later life obesity. Following an adverse ...
متن کاملFetal Thyroid Function, Birth Weight, and in Utero Exposure to Fine Particle Air Pollution: A Birth Cohort Study
BACKGROUND Thyroid hormones are critical for fetal development and growth. Whether prenatal exposure to fine particle air pollution (≤ 2.5 μm; PM2.5) affects fetal thyroid function and what the impact is on birth weight in normal healthy pregnancies have not been studied yet. OBJECTIVES We studied the impact of third-trimester PM2.5 exposure on fetal and maternal thyroid hormones and their me...
متن کاملPlacental DNA methylation as a proxy for fetal neurodevelopment and sex-specific associations with in utero particulate air pollution
Background and aims Exposure to particulate matter (PM) air pollution during pregnancy may affect human fetal development. Epigenetic mechanisms are believed to play an essential role in the developmental changes during early life. Within the ENVIRONAGE birth cohort, we investigated whether in utero exposure to PM is associated with differences in placental DNA methylation of genes involved in ...
متن کاملFetal growth and developmental programming.
The environment in utero and in early neonatal life may induce a permanent response in the fetus and the newborn, leading to enhanced susceptibility to later diseases. This review concentrates on the role and mechanisms of events during the antenatal and immediate postnatal period resulting in later life diseases, concentrating on abnormal growth patterns of the fetus. Fetal overgrowth is relat...
متن کاملAir pollution control with semi-infinite programming
Article history: Received 28 July 2007 Received in revised form 30 April 2008 Accepted 1 May 2008 Available online 9 May 2008
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ژورنال
عنوان ژورنال: Epigenomics
سال: 2017
ISSN: 1750-1911,1750-192X
DOI: 10.2217/epi-2017-0008